What does DNA do?
Table of the nucleic acid template patterns for the
formation of amino acids in protein sequences (from
wikipedia). These triplet patterns are formed from the four
bases U (uracil in RNAs), T (thymine in DNA), C (cytosine),
A (adenine), and G (guanine), and are often described as the
genetic ‘code’, but it is important to understand that this
usage of the word ‘code’ is metaphorical and can be
confusing.
A real code is an intentional encryption used by humans to
communicate. The genetic ‘code’ is not intentional in that
sense. The more neutral word ‘template’ is better. It also
expresses the fact that templates are used only when
required (activated), they are not themselves active causes.
DNA sequences are templates
for the formation of RNAs, some of which are in turn used as
templates for the formation of proteins. Only RNAs and
proteins are specified by the DNA sequences. RNAs and
proteins then cooperate with many metabolites and other
components of the organism to generate the numerous
interlocking biochemical pathways. These pathways in turn
work within the three dimensional structure of the cells,
tissues and organs of the body. But this three-dimensional
structure is not to be found in the one-dimensional DNA
sequences. How then do cells know how to form such an
intricate biological mechanism of precise functionality? The
answer is self-templating. The three-dimensional structures
copy themselves, first by growing in size and then, when the
cell becomes large enough to divide, the structures are
divided between the two cells. Each daughter cell therefore
inherits its complete complement of structure as well as
inheriting the genome.
For further aspects
of the answer to this question see
Immortal genes?
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The MUSIC of Life: Biology Beyond the Genome ©Denis Noble |